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α-Allyl-α-aryl α-Amino Esters in the Asymmetric Synthesis of Acyclic and Cyclic Amino Acid Derivatives by Alkene Metathesis

✍ Scribed by Curto, John M.; Kozlowski, Marisa C.


Book ID
124070563
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
790 KB
Volume
79
Category
Article
ISSN
0022-3263

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The electrophilic imino esters XF 2 CC(=NPG)CO 2 Me and imino phosphonates CF 3 CC(=NPG)P(O)(OR) 2 (PG = SO 2 Ph, Cbz, Boc) were transformed by nucleophilic and then electrophilic additions into fluorine-containing amino esters and amino phosphonates with two pendent alkene chains [Z = CO 2 Me, P(O