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Asymmetric Synthesis of α-Allyl-α-Aryl α-Amino Acids by Tandem Alkylation/π-Allylation of α-Iminoesters

✍ Scribed by Curto, John M.; Dickstein, Joshua S.; Berritt, Simon; Kozlowski, Marisa C.


Book ID
124052944
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
971 KB
Volume
16
Category
Article
ISSN
1523-7060

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Palladium-Catalyzed Asymmetric Allylic A
✍ Barry M. Trost; Gretchen M. Schroeder; Jesper Kristensen 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB 👁 1 views

The generation of quatenary chiral centers through catalytic asymmetric alkylation of ketone enolates has been the subject of investigation in recent years. [1] The palladiumcatalyzed asymmetric allylic alkylation (AAA) of prochiral nucleophiles represents one such strategy for the creation of quate