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Synthesis of Fluorine-Containing Cyclic α-Amino Acid and α-Amino Phosphonate Derivatives by Alkene Metathesis

✍ Scribed by Sergey N. Osipov; Oleg I. Artyushin; Alexey F. Kolomiets; Christian Bruneau; Michel Picquet; Pierre H. Dixneuf

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
341 KB
Volume
2001
Category
Article
ISSN
1434-193X

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✦ Synopsis

The electrophilic imino esters XF 2 CC(=NPG)CO 2 Me and imino phosphonates CF 3 CC(=NPG)P(O)(OR) 2 (PG = SO 2 Ph, Cbz, Boc) were transformed by nucleophilic and then electrophilic additions into fluorine-containing amino esters and amino phosphonates with two pendent alkene chains

[Z = CO 2 Me, P(O)(

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