ZD1839 (Gefitinib, ‘Iressa’), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma
✍ Scribed by Fuminori Teraishi; Shunsuke Kagawa; Takanori Watanabe; Yasuhisa Tango; Takeshi Kawashima; Tatsuo Umeoka; Masahiko Nisizaki; Noriaki Tanaka; Toshiyoshi Fujiwara
- Book ID
- 116465753
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 444 KB
- Volume
- 579
- Category
- Article
- ISSN
- 0014-5793
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## Abstract Selective tyrosine kinase inhibitors are regarded as promising antitumor agents for cancer treatment. Iressa® (ZD1839) is an orally active, selective EGFR‐TKI (epidermal growth factor receptor‐tyrosine kinase inhibitor) that blocks signal transduction pathways implicated in cancer cell
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