## Objective: To test a possible association between activated protein C resistance and intrauterine fetal death. Methods: The activated protein C anticoagulant activity and factor V R506Q mutation were assessed in 14 nonpregnant women with a history of intrauterine fetal death and 14 healthy cont
What is the impact of resistance to activated protein C (Leiden mutation to factor V) in inflammatory bowel disease?
โ Scribed by Emma Attvall; Attila Frigyesi; Berit Sternby
- Book ID
- 106059091
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 117 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0179-1958
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Background: Activated protein c (apc) resistance is the most frequently diagnosed heritable thrombophilic defect predisposing to thrombosis. ## Objectives: To determine the prevalence of apc resistance due to factor v leiden mutation in patients with leg ulcers. ## Methods: Within a 2-year-p
Hereditary predisposition to thrombosis due to activated protein C resistance (APCR) has been attributed to a missense mutation in the factor V gene at nucleotide 1691 (G to A), causing replacement of arginine at codon 506 with glutamine. Using an RFLP-PCR assay to detect this mutation, we measured