Detection of preferential NRAS mutations
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Dr. Sabyasachi Ganguly; Vundavalli V. V. S. Murty; Felipe Samaniego; Victor E. R
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Article
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1990
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John Wiley and Sons
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English
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We have studied 3 I male germ cell tumors (GCTs) for probable mutations in codons 12, 13, and 6 I of HRAS, KRAS, and NRAS oncogenes using the polymerase chain reaction. Twenty of the thirty-one tumors exhibited NRAS gene mutations, 14 in codon 6 I, and six in codon 12, whereas no mutations were dete