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The estimation of in vivo mutation rate and frequency from samples of human lymphocytes

✍ Scribed by Alexander A. Morley

Book ID
113194985
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
888 KB
Volume
357
Category
Article
ISSN
0027-5107

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nine resistant T-lymphocytes were isolated from two blood samples obtained 4 months apart from a 50year-old male subiect. Sixty-six of these mutants were characterized at the DNA sequence level using cDNA. One particular single base substitution was recovered a total of 23 fimes. The majority of T-c