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Molecular analysis of deletion mutations at the HPRT locus in CHO cells using the polymerase chain reaction

✍ Scribed by Z.D. Xu; Y. Yu; B.J.F. Rossiter; R.A. Gibbs; C.T. Caskey; A.W. Hsie


Book ID
113252191
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
84 KB
Volume
252
Category
Article
ISSN
0165-1161

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## Abstract We investigated whether the polymerase chain reaction (PCR) could be used to determine the mechanism of mutation in lymphocyte clones mutated at the HLA‐A locus. Three polymorphisms, at Factor XIIIA, D6S109, and intron 3 of the HLA‐A gene, were used to study a series of clones previousl