Use of trichlorodimethylethyl as a protecting group and tributylphosphine as a deprotecting agent in oligonucleotide synthesis
β Scribed by Letsinger, Robert L.; Groody, E. Patrick; Tanaka, Toshiki
- Book ID
- 126933388
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 288 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
2-Methylsulfonylethoxy dichlorophosphine has been converted into the mono-N-morpholino derivative and applied for the preparation of 5'-D,N-protected d-nucleoside-3'-phosphoramidites. The latter intermediates could be used in the presence of 1-hydroxyben~otriazole for the formation of 3'-5'-phosphot
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