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Use of the excluded protecting group (EPG) method for peptide synthesis

โœ Scribed by Head, D.B. ;Dong, J.Z. ;Burton, J.A.


Book ID
110893863
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
175 KB
Volume
65
Category
Article
ISSN
1397-002X

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract We have found a novel way of protecting the hydroxyl function in hydroxyโ€Lโ€amino acids, making use of the tโ€butoxy group, which is readily split by acids, but not by bases. This group is introduced by acidโ€catalysed addition of isobutene to Nโ€acylated hydroxyโ€Lโ€amino acids. The blockin