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Acetol: a useful new protecting group for peptide synthesis

✍ Scribed by Bijoy Kundu

Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
152 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis

Acetol can be conveniently used as a reagent for the protection of carboxylic acids in peptide synthesis. It has been found to be inert and stable to hydrogenolytic and acidolytic conditions normally used in peptide synthesis. Deblocking has been selectively achieved under mild conditions using Bu4NF.3H20 in THF.

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