Use of sodium iodide symporter expression in differentiated thyroid carcinomas
✍ Scribed by Elaine C. Morari; Marjory A. Marcello; Ana Carolina T. Guilhen; Lucas L. Cunha; Paulo Latuff; Fernando A. Soares; José Vassallo; Laura S. Ward
- Book ID
- 108704895
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 307 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0300-0664
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The sodium iodide symporter (NIS) mediates iodide uptake into the thyroid. Because of this mechanism, differentiated thyroid cancer is susceptible for radioiodine therapy. Functional NIS expression in extrathyroidal tumors has been reported mainly in breast cancer. We screened colorecta
## Abstract ## Objectives/Hypothesis: Sodium/iodide symporter (NIS) is a glycoprotein which is related to the concentration of radioiodine in thyroid cancer. Glucose transporter‐1 (Glut‐1) and hexokinases (HK) are glycoproteins related to glucose metabolism (i.e., uptake and phosphorylation) in va
## Abstract ## Background. Gene therapy that uses delivery of the sodium‐iodide symporter (NIS) gene followed by radioiodide administration has been proposed as a novel form of radiotherapy for nonthyroidal cancers. ## Methods. In vitro [^125^I] iodide accumulation and efflux from cells was dete