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Expression and localization of the sodium/iodide symporter (NIS) in testicular cells

✍ Scribed by Diego Russo; Angela Scipioni; Cosimo Durante; Elisabetta Ferretti; Loredana Gandini; Valentina Maggisano; Donatella Paoli; Antonella Verrienti; Giuseppe Costante; Andrea Lenzi; Sebastiano Filetti


Book ID
107571549
Publisher
Springer
Year
2011
Tongue
English
Weight
460 KB
Volume
40
Category
Article
ISSN
0969-711X

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✍ Andrew W. Gaut; Gang Niu; Kimberly J. Krager; Michael M. Graham; Douglas K. Tras πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 579 KB

## Abstract ## Background. Gene therapy that uses delivery of the sodium‐iodide symporter (NIS) gene followed by radioiodide administration has been proposed as a novel form of radiotherapy for nonthyroidal cancers. ## Methods. In vitro [^125^I] iodide accumulation and efflux from cells was dete

Endogenous expression of the sodium iodi
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## Abstract The sodium iodide symporter (NIS) mediates iodide uptake into the thyroid. Because of this mechanism, differentiated thyroid cancer is susceptible for radioiodine therapy. Functional NIS expression in extrathyroidal tumors has been reported mainly in breast cancer. We screened colorecta