Sodium Iodide Symporter and the Radioiodine Treatment of Thyroid Carcinoma
β Scribed by June-Key Chung; Hye Won Youn; Joo Hyun Kang; Ho Young Lee; Keon Wook Kang
- Book ID
- 107686970
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 271 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1869-3474
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π SIMILAR VOLUMES
## Abstract The discovery of functioning metastases of thyroid carcinoma and their appropriate treatment with radioiodine are the keys to longβterm survival. Functioning metastases can be adequately found only if postsurgical residual normal thyroid tissue is ablated and total body scanning perform
## Abstract The sodium iodide symporter (NIS) mediates iodide uptake into the thyroid. Because of this mechanism, differentiated thyroid cancer is susceptible for radioiodine therapy. Functional NIS expression in extrathyroidal tumors has been reported mainly in breast cancer. We screened colorecta
## Abstract ## Background. Gene therapy that uses delivery of the sodiumβiodide symporter (NIS) gene followed by radioiodide administration has been proposed as a novel form of radiotherapy for nonthyroidal cancers. ## Methods. In vitro [^125^I] iodide accumulation and efflux from cells was dete