✦ LIBER ✦

Use of shift reagent with MTPA derivatives in 1H NMR spectroscopy. II. determination of absolute configuration and diastereomeric composition of secondary carbinols in epimeric mixture

✍ Scribed by Shozo Yamaguchi; Fujiko Yasuhara

Publisher: Elsevier Science
Year: 1977
Tongue: French
Weight: 215 KB
Volume: 18
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)92558-4

No coin nor oath required. For personal study only.

✦ Synopsis

Determination of absolute configuration and optical purity of partially active secondary carbinols by NMR spectroscopy has been the subject of many investigations. l-3 However, configurational assignment of secondary carbinols in an epimeric mixture has so far been limited to the case where the definite configurational relationship of a hydroxyl group in question with a neighboring chiral center having known absolute stereochemistry can be established.

📜 SIMILAR VOLUMES

Use of shift reagent with diastereomeric

Use of shift reagent with diastereomeric MTPA esters for determination of configuration and enantiomeric purity of secondary carbinols in 1H NMR spectroscopy

✍ Shozo Yamaguchi; Fujiko Yasuhara; Kuninobu Kabuto 📂 Article 📅 1976 🏛 Elsevier Science 🌐 French ⚖ 477 KB

Use of shift reagent with MTPA derivativ

Use of shift reagent with MTPA derivatives in 1H NMR spectroscopy. IV. Determination of absolute configuration and enantiomeric purity of amino acid derivatives.

✍ Fujiko Yasuhara; Kuninobu Kabuto; Shozo Yamaguchi 📂 Article 📅 1978 🏛 Elsevier Science 🌐 French ⚖ 282 KB

Determination of absolute configuration and enantiomeric purity of d-amino acids using chemical shift nonequivalence has been well investigated, 132 while little was reported3 on the successful application correlating the absolute configuration of amino acids with their relative magnitude of lanthan

Use of shift reagent with mtpa derivativ

Use of shift reagent with mtpa derivatives in 19F NMR spectroscopy: III. Determination of absolute configuration and enantiomeric purity of secondary alcohols

✍ A. J. De Van Wal; E. M. Merckx; G. L. Lemière; T. A. van Osselaer; J. A. Lepoivr 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 306 KB 👁 2 views

The LIS values produced by Eu(fodJ3 for the CF3-19F NMR signals of the MlTA e s t e r s of different stereoisomeric secondary alcohols have been measured. The applicability o f these values for assigning the absolute configuration of the alcohols has been studied. The advantages of t h i s method ov

Use of shift reagent with MTPA derivativ

Use of shift reagent with MTPA derivatives in 1H NMR spectroscopy. III. Determination of absolute configuration and enantiomeric purity of primary carbinols with chiral center at the C-2 position

✍ Fujiko Yasuhara; Shozo Yamaguchi 📂 Article 📅 1977 🏛 Elsevier Science 🌐 French ⚖ 247 KB

Use of Shift Reagent with MTPA Derivativ

Use of Shift Reagent with MTPA Derivatives in 19F NMR Spectroscopy: Determination of Absolute Configuration of Stereomeric 2- and 3- Substituted Cyclohexanols

✍ E. M. Merckx; A. J. Van De Wal; J. A. Lepoivre; F. C. Alderweireldt 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 210 KB 👁 2 views

Determination of absolute configuration

Determination of absolute configuration of trans-2-arylcyclohexanols using remarkable aryl-induced 1H NMR shifts in diastereomeric derivatives

✍ Masato Matsugi; Kinuyo Itoh; Masatomo Nojima; Yuri Hagimoto; Yasuyuki Kita 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 110 KB

A facile determination of the absolute configuration of trans-2-arylcyclohexanols was achieved. It takes advantage of the observations of the remarkable aryl-induced 1 H NMR shifts that seems to be ascribable to the discrimination of the diastereo-environment between intermediary optically active di