Use of “lipophilic” Sephadex in peptide synthesis
✍ Scribed by Viktor Mutt; Ernst Nyström; Jan Sjövall
- Book ID
- 108337658
- Publisher
- Elsevier Science
- Year
- 1966
- Tongue
- English
- Weight
- 304 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1873-3778
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📜 SIMILAR VOLUMES
Practical procedures have been developed for synthesis of peptides using lipases and esterases as catalysts. We describe here a new strategy for enzymatic peptide synthesis using an esterase without amidase activity as a catalyst and N-acyl amino acid esters and amino acid esters as substrates in e
## Abstract __N,N__′‐Carbonyldi‐s‐triazole is shown to be a useful peptide‐forming reagent. Advantages over other reagents are: (1) low degree of racemization, (2) applicability in dimethylformamide, a solvent for both small and large peptides.