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Polymer support oligonucleotide synthesis VII use of Sephadex LH 20

✍ Scribed by H. Köster; K. Heyns


Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
219 KB
Volume
13
Category
Article
ISSN
0040-4039

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Polymer support oligonucleotide synthesi
✍ H. Köster 📂 Article 📅 1972 🏛 Elsevier Science 🌐 French ⚖ 189 KB

Various methoda for the ryntherir of oligonucleotidee on polymeric carriers are in progreea in thim laboratory. We first used makroporous, nonswellable polystyrene 1, 3. 5) and were able to synthesize dT(pdT), and dTpdTpdApdCpdCpdTpdA 4,6) . In another study we used popcorn polyetyrene for the synth

Polymer support oligonucleotide synthesi
✍ H. Köster; A. Stumpe; A. Wolter 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 277 KB

The rapid and efficient synthesis of d(TTTATT) and d(CATGAGGAAGT) on glass beads of controlled pore size using N-acylated 5'-O-trityldeoxynucleoside-3'-(2-chloro)-phenyl phosphates as phosphate components, capping with acetic anhydride, detritylation with ZnBr2 and 1-(mesitylene-2-sulphonyl)-3-nitro