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Use of a Dual-Marker Form of Analysis to Estimate Binding Constants Between Receptors and Ligands by Affinity Capillary Electrophoresis

✍ Scribed by V. Villareal; A. Brown; A. Gomez; C. F. Silverio; F. A. Gomez


Book ID
111788121
Publisher
Springer
Year
2004
Tongue
English
Weight
371 KB
Volume
60
Category
Article
ISSN
0009-5893

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Estimation of Receptor–Ligand Interactio
✍ Erica Mito; Ying Zhang; Sally Esquivel; Frank A. Gomez πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 95 KB

The study of receptor-ligand interactions by affinity capillary electrophoresis (ACE) requires an accurate form of analysis. Here, we examine the use of two noninteracting standards (markers) in the analysis of binding constant data in ACE studies. This concept is demonstrated using two model system