The 1,1,1,3,3,3-Hexafluoro-2-propyl group can be used as a new class of phosphate protecting group for the protecting group of internucleotidic bonds in the oligonucleotide synthesis by the phosphotriester approach . This protecting group is removed easily by treatment with 0 .3 M N 1 ,N 1 ,N 3 ,N''
Use of 1,1,1,3,3,3-hexafluoro-2-propyl protecting group in the synthesis of dna fragments via phosphoramidite intermediates
โ Scribed by Hiroshi Takaku; Tetsuo Watanabe; Shoji Hamamoto
- Book ID
- 107858381
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 536 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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