## Abstract Rats were injected with 120 ΞΌCi of ^14^Cβacetaldehyde containing carrier acetaldehyde, and the urinary excretion products were assayed by cation exchange chromatography, resolving five main peaks of radioactivity. Urine contained 6% of the dose of ^14^Cβacetaldehyde administered. The ma
Urinary excretion of chlorothiazide in rats before and after phenobarbitone administration
β Scribed by E. E. Ohnhaus
- Book ID
- 112653220
- Publisher
- Springer
- Year
- 1972
- Tongue
- English
- Weight
- 184 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1420-682X
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The elimination of phenobarbitone (PB) was studied in 14 chronically treated epileptic patients under steady state conditions. PB, [S]-PB-N-glucoside ( [S]-PB-N-G) and p-hydroxy-PB (p-OH-PB) were assayed in urine by a HPLC method. Some 57 % of the daily dose was recovered in urine, 14 % as [S]-PB-N