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Uptake of 11C-labeled prostaglandin D2 into monkey brain by positron emission tomography study

✍ Scribed by Watanabe, Yasuyoshi; Langstrom, Bengt; Yumoto, Noboru; Hatanaka, Michiyo; Watanabe, Yumiko; Hayashi, Hideya; Hayaishi, Osamu


Book ID
122081983
Publisher
Elsevier Science
Year
1987
Weight
82 KB
Volume
5
Category
Article
ISSN
0921-8696

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By means of positron emission tomography the uptake and kinetics of N-(methyl-11C)clozapine in different brain regions have been studied in Rhesus monkeys. 11C-clozapine rapidly entered the brain and maximum radioactive uptake was seen 5-12 min after administration. Highest uptake was measured in th