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214 Brain uptake of 11C-labelled stable prostacyclin receptor ligand and studied by positron emission tomography

✍ Scribed by Yasuyoshi Watanabe; Masaaki Suzuki; Margareta Bjorkman; Kiyoshi Matsumura; Koichi Kato; Yumiko Watanabe; Hirotaka Onoe; Hisashi Doi; Ryoji Noyori; Bengt Langstrom


Book ID
119522993
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
90 KB
Volume
28
Category
Article
ISSN
0168-0102

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By means of positron emission tomography the uptake and kinetics of N-(methyl-11C)clozapine in different brain regions have been studied in Rhesus monkeys. 11C-clozapine rapidly entered the brain and maximum radioactive uptake was seen 5-12 min after administration. Highest uptake was measured in th