Untersuchungen der Thrombocytenaggregation und der Gerinnselretraktion bei reifen und unreifen Neugeborenen
✍ Scribed by Maak, B. ;Frenzel, J. ;Rogner, G.
- Publisher
- Springer-Verlag
- Year
- 1972
- Weight
- 769 KB
- Volume
- 111
- Category
- Article
- ISSN
- 0044-2917
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✦ Synopsis
The aggregation of blood platelets and the retraction of the clot were measured during the first 21 days of life in the blood of premature and newborn infants. The results were compared with those of children at the age of 6 to 14 years. At first the aggregation of blood platelets is diminished in premature and newborn infants in comparison with the results of school children. But in the period of 3 weeks of investigation a rise in the platelet aggregation is seen.
The clot retraction of newborn babies in the first days of life is the same as in healthy school children. After this time the weight of the clot rises in premature and mature newborn infants. The reason for diminished clot retraction is thought to be a high number of young platelets among the whole population of blood platelets.
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Platelet counts and platelet adhesiveness were investigated in 127 premature and 149 full term newborn infants during the first 21 days of life. Platelet counts were obtained simultaneously in venous and capillary blood. Platclet adhesiveness was studied by the methods of ~u and Breddin. The results
In 70 newborns, mostly premature infants suffering from apnea, a simultaneous monitoring of ECG and apnea was carried out. 67~ of the infants showed cardiac arrythmias, mainly sinusbradycardia and atrioventricular block, in apnea. The causes of arrhythmias are discussed.
An der Stelle der Gefal~wandverletzung kommt es zur Adhasion, Agglomeration und zur Lyse der Pl~ttchen, ein Vorgang, der yon EBERTIt U. SCttIMMELBUSCtt 17 bereits 1886 als ,,vise6se Metamorphose" bezeichnet wurde. Durch diese Ver~nderungen kommt es zur Bildung eines Plattehenpfropfes, der den primar