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Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment

✍ Scribed by Tarek, Nidale; Le Luduec, Jean-Benoit; Gallagher, Meighan M.; Zheng, Junting; Venstrom, Jeffrey M.; Chamberlain, Elizabeth; Modak, Shakeel; Heller, Glenn; Dupont, Bo; Cheung, Nai-Kong V.; Hsu, Katharine C.

Book ID
115477894
Publisher
American Society for Clinical Investigation
Year
2012
Tongue
English
Weight
785 KB
Volume
122
Category
Article
ISSN
0021-9738

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New anti-GD2 monoclonal antibodies produ
New anti-GD2 monoclonal antibodies produced from gamma-interferon-treated neuroblastoma cells
✍ Nicole Gross; Daniel Beck; Jacques Portoukalian; Simone Favre; Stefan Carrel πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 French βš– 844 KB

Three monoclonal antibodies (IgG,) have been produced from hybridomas obtained by fusion of murine myeloma cells and spleen cells of mice hyperimmunized with gammainterferon-treated neuroblastoma cells. The 3 MAbs, 7A4, 2A6 and IG8, detected an antigen present on neuroblastoma tumors and cell lines,