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Treatment of high-risk neuroblastoma with anti-GD2 antibodies

✍ Scribed by Victoria Castel; Vanessa Segura; Adela Cañete

Book ID
107597737
Publisher
Springer Milan
Year
2010
Tongue
Spanish
Weight
282 KB
Volume
12
Category
Article
ISSN
1699-048X

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Immunotherapeutic strategies in neurobla
Immunotherapeutic strategies in neuroblastoma: Antitumoral activity of deglycosylated ricin A conjugated anti-GD2 antibodies and anti-CD3xanti-GD2 bispecific antibodies
✍ Manzke, Oliver ;Russello, Orsolina ;Leenen, Christiane ;Diehl, Volker ;Bohlen, H 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 393 KB

Background. The antigen GD2 is selectively expressed on the surface of neuroblastoma cells, and is detected by the monoclonal antibody BW704. In this study, we describe the antitumoral capacity of the immunotoxin BW704dgA (BW704 conjugated to deglycosylated ricin A), and of anti-CD3xanti-GD2 bispeci