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Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

✍ Scribed by Yu, Alice L.; Gilman, Andrew L.; Ozkaynak, M. Fevzi; London, Wendy B.; Kreissman, Susan G.; Chen, Helen X.; Smith, Malcolm; Anderson, Barry; Villablanca, Judith G.; Matthay, Katherine K.; Shimada, Hiro; Grupp, Stephan A.; Seeger, Robert; Reynolds, C. Patrick; Buxton, Allen; Reisfeld, Ralph A.; Gillies, Steven D.; Cohn, Susan L.; Maris, John M.; Sondel, Paul M.

Book ID
125464163
Publisher
Massachusetts Medical Society
Year
2010
Tongue
English
Weight
357 KB
Volume
363
Category
Article
ISSN
0096-6762

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Immunotherapeutic strategies in neurobla
Immunotherapeutic strategies in neuroblastoma: Antitumoral activity of deglycosylated ricin A conjugated anti-GD2 antibodies and anti-CD3xanti-GD2 bispecific antibodies
✍ Manzke, Oliver ;Russello, Orsolina ;Leenen, Christiane ;Diehl, Volker ;Bohlen, H πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 393 KB

Background. The antigen GD2 is selectively expressed on the surface of neuroblastoma cells, and is detected by the monoclonal antibody BW704. In this study, we describe the antitumoral capacity of the immunotoxin BW704dgA (BW704 conjugated to deglycosylated ricin A), and of anti-CD3xanti-GD2 bispeci