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Unexpectedly low prevalence of intracerebral hemorrhages in sporadic cerebral amyloid angiopathy

✍ Scribed by J. Attems; F. Lauda; K. A. Jellinger


Publisher
Springer
Year
2008
Tongue
English
Weight
323 KB
Volume
255
Category
Article
ISSN
0340-5354

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Matrix metalloproteinase–9 and spontaneo
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We examined the potential role of the extra-cellular matrix-degrading enzyme, matrix metalloproteinase-9 (MMP-9), in the pathogenesis of cerebral amyloid angiopathy (CAA)-induced spontaneous hemorrhage. The amyloid-beta peptide (Abeta) induced the synthesis, release and activation of MMP-9 in murine