THYROXINE 1741) T3 UPTAKE(T3U) FREE THYROXINE FREE THYROXINE PLRCtRT INDEX (Fll) EOUIVALENT(FTE) UNITS UNITS w / d l 45 I 14 0 12 0 I + , ; , 6 0 i z 2 0 p<OOS CONTROL OPH
Spatial distribution of hemorrhages in cerebral amyloid angiopathy
β Scribed by Kurt A. Jellinger
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 40 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0364-5134
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## Abstract Cerebral amyloid angiopathy (CAA) results from deposition of Ξ²βamyloid in the media and adventitia of small arteries and capillaries of the leptomeninges and cerebral cortex and is a major cause of lobar intracerebral hemorrhage and cognitive impairment in the elderly. CAA is associated
We examined the potential role of the extra-cellular matrix-degrading enzyme, matrix metalloproteinase-9 (MMP-9), in the pathogenesis of cerebral amyloid angiopathy (CAA)-induced spontaneous hemorrhage. The amyloid-beta peptide (Abeta) induced the synthesis, release and activation of MMP-9 in murine