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Understanding the molecular pathogenesis of acute promyelocytic leukemia

✍ Scribed by Lo-Coco, Francesco; Hasan, Syed Khizer

Book ID
121892526
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
392 KB
Volume
27
Category
Article
ISSN
1521-6926

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Acute Promyelocytic Leukemia (APL) is a distinct subtype of myeloid leukemia that in the USA alone affects more than 3,000 individuals every year. APL is characterized by three distinct and unique features: i) the accumulation in the bone marrow of tumor cells with promyelocytic features; ii) the in

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