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The molecular pathogenesis of acute myeloid leukemia

✍ Scribed by Björn Steffen; Carsten Müller-Tidow; Joachim Schwäble; Wolfgang E. Berdel; Hubert Serve

Book ID: 108110039
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 709 KB
Volume: 56
Category: Article
ISSN: 1040-8428
DOI: 10.1016/j.critrevonc.2004.10.012

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Acute Promyelocytic Leukemia (APL) is a distinct subtype of myeloid leukemia that in the USA alone affects more than 3,000 individuals every year. APL is characterized by three distinct and unique features: i) the accumulation in the bone marrow of tumor cells with promyelocytic features; ii) the in