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Ubiquitin–proteasome system dysfunction in Parkinson’s disease: current evidence and controversies

✍ Scribed by Lim, Kah-Leong

Book ID
118277260
Publisher
Expert Reviews
Year
2007
Tongue
English
Weight
585 KB
Volume
4
Category
Article
ISSN
1478-9450

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Ubiquitin–proteasome system and Parkinson's disease
✍ C. Warren Olanow; Kevin St. P. McNaught 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

## Abstract Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin–proteasome system (UPS) to clear unwanted proteins, resulting in protein