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Ubiquitin–proteasome system and Parkinson's diseases

✍ Scribed by Ranjita Betarbet; Todd B. Sherer; J. Timothy Greenamyre


Book ID
116458375
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
288 KB
Volume
191
Category
Article
ISSN
0014-4886

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Ubiquitin–proteasome system and Parkinso
✍ C. Warren Olanow; Kevin St. P. McNaught 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

## Abstract Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin–proteasome system (UPS) to clear unwanted proteins, resulting in protein