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Two-year toxicity and carcinogenicity study of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07), a novel dual-function microbicide

✍ Scribed by Osmond J D’Cruz; Douglas Erbeck; Barbara Waurzyniak; Fatih M Uckun


Book ID
119419055
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
84 KB
Volume
78
Category
Article
ISSN
1556-5653

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## Abstract __5‐bromo‐6‐methoxy‐5,6‐dihydro‐3^′^‐azidothymidine‐5^′^‐(p‐bromophenyl) methoxyalaninyl phosphate__ (WHI‐07), a novel bromo‐methoxy‐substituted aryl phosphate derivative of zidovudine (ZDV), is a potent dual‐function contraceptive agent with anti‐HIV activity. Its potential for reprodu