✦ LIBER ✦

Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in B6C3F1 mice

✍ Scribed by Osmond J D’Cruz; Barbara Waurzyniak; Seang H Yiv; Fatih M Uckun

Book ID: 117085029
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 142 KB
Volume: 61
Category: Article
ISSN: 0010-7824
DOI: 10.1016/s0010-7824(99)00118-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Evaluation of subchronic (13-week) and r

Evaluation of subchronic (13-week) and reproductive toxicity potential of intravaginal gel–microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound whi-07) in B6C3F1 mice

✍ Osmond J. D'Cruz; Barbara Waurzyniak; Seang H. Yiv; Fatih M. Uckun 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 75 KB 👁 1 views

Lack of subchronic and reproductive toxi

Lack of subchronic and reproductive toxicity of intravaginal gel formulations of spermicidal vanadocenes in a 13-week study in B6C3F1 and CD-1 mice.

✍ O.J D’Cruz; F.M Uckun 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 35 KB

Lack of adverse effects on fertility of

Lack of adverse effects on fertility of female cd-1 mice exposed to repetitive intravaginal gel–microemulsion formulation of a dual-function anti-HIV agent: aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07)

✍ Osmond J. D'Cruz; Fatih M. Uckun 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB

## Abstract __5‐bromo‐6‐methoxy‐5,6‐dihydro‐3^′^‐azidothymidine‐5^′^‐(p‐bromophenyl) methoxyalaninyl phosphate__ (WHI‐07), a novel bromo‐methoxy‐substituted aryl phosphate derivative of zidovudine (ZDV), is a potent dual‐function contraceptive agent with anti‐HIV activity. Its potential for reprodu