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Two New Polyoxygenated Triterpenoids from Actinidia valvata

✍ Scribed by Hai-Liang Xin; Xiao-Qiang Yue; Yan-Feng Xu; Ying-Chun Wu; Ya-Ni Zhang; Yong-Zi Wang; Chang-Quan Ling

Publisher: John Wiley and Sons
Year: 2008
Tongue: German
Weight: 168 KB
Volume: 91
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200890060

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✦ Synopsis

Abstract

Two new polyoxygenated triterpenoids, (2__β__,3__α__,6__α__)‐2,3,6,20,23,30‐hexahydroxyurs‐12‐en‐28‐oic acid (1) and (2__β__,3__α__)‐2,3,20,23,24,30‐hexahydroxyurs‐12‐en‐28‐oic acid O‐β‐D‐glucopyranosyl ester (2) were isolated from the roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both compounds showed moderate cytotoxic activity in vitro against the BEL‐7402 and SMMC‐7721 tumor cell lines.

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