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Two New Pentacyclic Triterpenoids from Centella asiatica

✍ Scribed by Xiao-Xiang Weng; Jing Zhang; Wen Gao; Liang Cheng; Yan Shao; De-Yun Kong

Publisher
John Wiley and Sons
Year
2012
Tongue
German
Weight
185 KB
Volume
95
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two new pentacyclic triterpenoids, named centelloside D (1) and centelloside E (9), together with the seven known compounds 2–8, were isolated from the whole plants of Centella asiatica. Compound 5 was reported for the first time from this genus. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D‐ and 2D‐NMR, and HR‐MS experiments, and by comparison with literature data. Compounds 1–4, 6, and 8 did not show any cytotoxicity against L929 (mouse embryonic fibroblast).

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