Two New Disulfated Triterpenoids from Zygophyllum fabago

✍ Scribed by Saleha S. Khan; Afsar Khan; Amir Ahmed; Viqar U. Ahmad; Umar Farooq; Saima Arshad; Sadia Bader; Aqib Zahoor; Imran N. Siddiqui; Bilge Sener; Nurgun Erdemoglu

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: German
• Weight: 160 KB
• Volume: 93
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200900477

✦ Synopsis

From the aerial parts of Zygophyllum fabago, two new monosodium salts of sulfated derivatives of ursolic acid, along with two known quinovic acid glycosides were isolated. The structures of the new compounds were determined as (3b,4a)-3,23,30-trihydroxyurs-20-en-28-al 3,23-di(sulfate) sodium salt (1 : 1) (1) and of (3b,4a)-3,23,28-trihydroxyurs-20-en-30-yl b-d-glucopyranoside 3,23-di(sulfate) sodium salt (1 : 1) (2) with the molecular formula C 30 H 47 NaO 10 S 2 and C 36 H 59 NaO 15 S 2 , respectively. The structures of the known compounds were 3-O-( 2-O-sulfo-b-d-quinovopyranosyl)quinovic acid 28-b-d-glucopyranosyl ester (3) and 3-O-(b-d-glucopyranosyl)quinovic acid 28-b-d-glucopyranosyl ester ( 4) (quinovic acid ¼ (3b)-3-hydroxyurs-12-ene-27,28-dioic acid). The structures of all these compounds were determined by using 1D-and 2D-NMR spectroscopic techniques.