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New Polyoxygenated Triterpenoids from Stachyurus himalaicus var. himalaicus

✍ Scribed by Jing-Hua Yang; Yun-Song Wang; Rong Huang; Shi-De Luo; Hong-Bin Zhang; Liang Li


Publisher
John Wiley and Sons
Year
2006
Tongue
German
Weight
82 KB
Volume
89
Category
Article
ISSN
0018-019X

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✦ Synopsis


Two new polyoxygenated triterpenoids, stachlic acid A (= (2a,3b)-2,3,23,29-tetrahydroxyolean-12en-28-oic acid; 1) and stachlic acid B (= (2a,3a)-2,29-dihydroxy-3,23-[(1,1-dimethylmethylene)dioxy]olean-12-ene-28-oic acid; 2), were isolated from Stachyurus himalaicus var. himalaicus. Their structures were established by means of extensive spectroscopic studies and chemical evidence. The purified product 1 was found to have moderate in vitro cytotoxic activity against human Hela cells.


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