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Two mechanisms of antimutagenicity of the aminothiols cysteamine and WR-1065 in Saccharomycescerevisiae

โœ Scribed by G.R Hoffmann; R.A Shorter; J.L Quaranta; P.D McMaster

Book ID
117587985
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
138 KB
Volume
13
Category
Article
ISSN
0887-2333

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โœ Hoffmann, George R. ;Quaranta, Joseph L. ;Shorter, Rose A. ;Littlefield, L. Gayl ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 991 KB

The cancer chemotherapy drug bleomycin (BLM) is a potent inducer of genetic damage in a wide variety of assays. The radioprotectors cysteamine (CSM) and WR-1065 have been shown in previous studies to potentiate the induction of micronuclei and chromosome aberrations by BLM in Go human lymphocytes. B