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Modulation of the clastogenic activity of ionizing radiation and bleomycin by the aminothiol WR-1065

✍ Scribed by L. Gayle Littlefield; George R. Hoffmann


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
475 KB
Volume
22
Category
Article
ISSN
0893-6692

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The cancer chemotherapy drug bleomycin (BLM) is a potent inducer of genetic damage in a wide variety of assays. The radioprotectors cysteamine (CSM) and WR-1065 have been shown in previous studies to potentiate the induction of micronuclei and chromosome aberrations by BLM in Go human lymphocytes. B

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