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The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065

โœ Scribed by Alan M. Diamond; Phylis Dale; Judith L. Murray; David J. Grdina

Book ID
113194932
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
839 KB
Volume
356
Category
Article
ISSN
0027-5107

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The cancer chemotherapy drug bleomycin (BLM) is a potent inducer of genetic damage in a wide variety of assays. The radioprotectors cysteamine (CSM) and WR-1065 have been shown in previous studies to potentiate the induction of micronuclei and chromosome aberrations by BLM in Go human lymphocytes. B