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Tumor necrosis factor-α promoter polymorphisms in Mexican patients with systemic lupus erythematosus (SLE)

✍ Scribed by Zúñiga, J; Vargas-Alarcón, G; Hernández-Pacheco, G; Portal-Celhay, C; Yamamoto-Furusho, J K; Granados, J

Book ID
110037330
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
90 KB
Volume
2
Category
Article
ISSN
1466-4879

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The polymorphic tumor necrosis factor a (TNFa) gene encodes a cytokine involved in inflammation, angiogenesis, and apoptosis. One polymorphic variant is associated with increased production of TNFa. This study examined the frequency of this polymorphic variant in African-American patients with syste