Objective. To study the genetic association of interleukin-10 (IL-10) promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus (SLE), and to investigate possible associations with clinical manifestations of the disease. Methods. DNA was extracted from 88 Chinese patient
✦ LIBER ✦
IκBαPromoter Polymorphisms in Patients with Systemic Lupus Erythematosus
✍ Scribed by Chia-Hui Lin; Shu-Chen Wang; Tsan-Teng Ou; Ruei-Nian Li; Wen-Chan Tsai; Hong-Wen Liu; Jeng-Hsien Yen
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 215 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0271-9142
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## Abstract We have found subnormal amounts of chemotactic activity in zymosan‐treated sera from 13 of 29 patients with systemic lupus erythematosus (SLE). As an explanation for this abnormality, the presence of a uniquely specific, heat‐stable inhibitor of complement (C5)‐derived chemotactic activ