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Tumor necrosis factor alpha promoter polymorphism −308 G/A in Brazilian patients with systemic lupus erythematosus

✍ Scribed by Hildson Dornelas Angelo; Helker Albuquerque da Silva; Nadja Maria Jorge Asano; Maria Tereza Cartaxo Muniz; Maria de Mascena Diniz Maia; Paulo Roberto Eleutério de Souza


Book ID
119257583
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
235 KB
Volume
73
Category
Article
ISSN
0198-8859

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The polymorphic tumor necrosis factor a (TNFa) gene encodes a cytokine involved in inflammation, angiogenesis, and apoptosis. One polymorphic variant is associated with increased production of TNFa. This study examined the frequency of this polymorphic variant in African-American patients with syste