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Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

✍ Scribed by Dong, Haidong; Strome, Scott E.; Salomao, Diva R.; Tamura, Hideto; Hirano, Fumiya; Flies, Dallas B.; Roche, Patrick C.; Lu, Jun; Zhu, Gefeng; Tamada, Koji; Lennon, Vanda A.; Celis, Esteban; Chen, Lieping

Book ID: 109933177
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 788 KB
Volume: 8
Category: Article
ISSN: 1078-8956
DOI: 10.1038/nm730

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## RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is present in neoplastic cells, induces apoptosis of natural killer (NK)/T cells and plays a role in immune evasion. Fas ligand (FasL) is considered to have similar roles. The Epstein-Barr virus (EBV)-encoded latent membrane protein