## Abstract ## Background and Objectives The B7‐H1/PD‐1 pathway has recently been found to contribute to immune evasion of cancer cells from host immune system. This study aimed to investigate the expression of B7‐H1 and its receptor PD‐1 and to explore their significance in the progression of int
✦ LIBER ✦
Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy
✍ Scribed by Christian Blank; Thomas F. Gajewski; Andreas Mackensen
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 342 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0340-7004
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## Abstract ## Background CGβ is expressed not only in placenta, but also in a wide range of tumors. To study DNA vaccine based on xenogeneic CGβ for cancer immuno‐therapy, we investigated whether rhesus monkey CGβ (rmCGβ) DNA vaccine could induce protective T‐cell responses and humoral responses