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Co-inhibitory role of T-cell-associated B7-H1 and B7-DC in the T-cell immune response

✍ Scribed by Su-Kil Seo; Hyoun-Mi Seo; Hye-Young Jeong; Il-Whan Choi; Yeong-Min Park; Hideo Yagita; Lipieng Chen; In-Hak Choi


Book ID
108152268
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
320 KB
Volume
102
Category
Article
ISSN
0165-2478

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## Abstract Human tumors frequently escape immune destruction, despite the presence of cyototoxic T cells (CTL) recognizing tumor‐associated antigens (TAA). We have previously shown that programmed death ligand‐1 (PD‐L1), a recently identified ligand of the B7 superfamily, is expressed on murine tu