B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis
β Scribed by Keith M. Hamel; Yanxia Cao; Yumei Wang; Rachel Rodeghero; Tamas Kobezda; Lieping Chen; Alison Finnegan
- Book ID
- 102824917
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 613 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0014-2980
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T cell co-stimulation through the CD28 receptor on T cells is critical to the induction of experimental autoimmune encephalomyelitis (EAE). In this study, expression of the co-stimulatory ligands B7-1 (CD80) and B7-2 (CD86), as well as the receptors CD28 and CTLA-4, were quantitated in central nervo
It is now well recognized that a large proportion of cases with acute lymphoblastic leukemia are classified as non-T/non-B neoplastic disease. The origin of leukemic non-Thon-B cells is at present not known. It has been shown that fresh or cultured leukemic T lymphoblasts exert no stimulating capaci