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Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease

✍ Scribed by M. I. Torres; M. A. López-Casado; P. Lorite; A. Ríos

Book ID
108699594
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
597 KB
Volume
148
Category
Article
ISSN
0009-9104

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## Abstract The first and rate‐limiting step of the kynurenine pathway, in which tryptophan (Trp) is converted to __N__‐formylkynurenine is catalyzed by two heme‐containing proteins, Indoleamine 2,3‐dioxygenase (IDO), and Tryptophan 2,3‐dioxygenase (TDO). In mammals, TDO is found exclusively in liv