Tritium-labelling of Natural Products
β Scribed by MAURER, RAINER; WENZEL, MARTIN; KARLSON, PETER
- Book ID
- 109635872
- Publisher
- Nature Publishing Group
- Year
- 1964
- Tongue
- English
- Weight
- 343 KB
- Volume
- 202
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/202896b0
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π SIMILAR VOLUMES
## Abstract Tritiumβlabelled lipid preparations are obtained by heterogeneous isotopic exchange with gaseous tritium in solution. After appropriate purification, the localization of the label was determined in the main fragments of [^3^H]βcompounds. The obtained data on specific radioactivity and t
## Abstract The synthesis of tritium labelled nitroaryldihydropyridines was achieved by dehalogenation of a brominated precursor using the palladium hydroxide on charcoal as catalyst. The investigations described show the example [^3^H]nimodipine which was prepared with a specific activity of 16,4
## Abstract Mannitol, galactitol and myoβinositol were labelled by a solid state isotope exchange with gaseous tritium. The labelled polyois were prepared with specific activities in the range 740β4440 TBq/mol (20β120 kCi/mol) after purification by HPLC.
## Abstract Attempts to reach phenothiazine derivatives labelled with tritium at high specific activity, are described. All the syntheses are based on catalysed dehalogenation procedures. The most encouraging results are those obtained by halogenation of the desired compound followed by catalytic d